WebUses Ertapenem is used to prevent and treat a wide variety of bacterial infections. This medication is known as a carbapenem-type antibiotic. It works by stopping the growth of … WebIntroduction. Valproic acid (VPA) overdose most commonly presents with gradations of central nervous system (CNS) depression, but in the most severe forms can lead to fatal cerebral edema and coma. 1-3 Typical management includes supportive therapy and consideration of carnitine supplementation or dialysis. We present a case of massive …
Ertapenem Uses, Side Effects & Warnings - Drugs.com
WebCarbapenems (CBPs), such as imipenem/cilastatin, meropenem, ertapenem, and doripenem, have a broad antimicrobial spectrum and are used to treat severe and complicated bacterial infections . The interaction between CBPs and valproic acid (VPA), which is a broad-spectrum AED and widely used for acute and chronic seizures ... WebMar 1, 2024 · The analysis of the VPA–ertapenem drug interaction showed a mean reduction of 71% (range, 38–98%) of VPA co-concentrations. ... Interaction of valproic acid and carbapenem antibiotics with multidrug resistance-associated proteins in rat erythrocyte membranes. Epilepsy Res, 71 (2006), pp. 76-87. gunilla westin trosa
UpToDate
WebThe amount of valproic acid in your blood may decrease. If you are taking valproic acid for epilepsy, your seizures may not be controlled. What you should do about this interaction: WebA Critical Interaction Between Ertapenem and Valproic Acid. Molnar, Gabor P. DO; Stephens, Kyle J. MD; George, Lauren V. PharmD, BCPS; Stewart, Jonathan T. MD, … WebThe concomitant use of ertapenem and valproic acid/divalproex sodium is generally not recommended. Anti-bacterials other than ... 7 DRUG INTERACTIONS . 7.1 Probenecid . 7.2 Valproic Acid . 8 USE IN SPECIFIC POPULATIONS . 8.1 . Pregnancy 8.2 . Labor and Delivery 8.3 . Nursing Mothers 8.4 . Pediatric Use 8.5 . Geriatric Use gunilla westergren-thorsson