WebDec 1, 2024 · Metronidazole is one of the mainstay drugs for the treatment of anaerobic infections [ 1,2 ]. It is approved by the US Food and Drug Administration for the treatment of anaerobic and protozoal infections. Metronidazole exerts its antimicrobial effects through the production of free radicals that are toxic to the microbe. WebRenal Impairment. Decreased renal function does not alter the single-dose pharmacokinetics of metronidazole. Subjects with end-stage renal disease (ESRD; CL CR =8.1±9.1 mL/min) and who received a single intravenous infusion of metronidazole 500 mg had no significant change in metronidazole pharmacokinetics but had 2-fold higher …
Flagyl 400mg Tablets - Summary of Product Characteristics
WebFLAGYL prescription and dosage sizes information for physicians and healthcare professionals. ... Severe hepatic impairment: reduce dose by 50%. Hemodialysis: consider dose supplementation after ... WebApr 1, 2024 · For oral dosage forms (capsules or tablets): For amebiasis infections: Adults—500 or 750 milligrams (mg) 3 times a day for 5 to 10 days. Children—Dose is … dwayne johnson daughters age
METRONIDAZOLE - Food and Drug Administration
WebMetronidazole is an antibiotic that is used to treat bacterial infections of the vagina, stomach, liver, skin, joints, brain and spinal cord, lungs, heart, or bloodstream. We … WebSystemically administered metronidazole is significantly removed (up to 65% of a dose) during a standard hemodialysis session. In pediatric patients, a dose of 4 mg/kg/dose IV/PO every 6 hours is recommended (based on usual dose of 15 to 30 mg/kg/day divided every 6 to 8 hours). Peritoneal dialysis No dosage adjustment is necessary in adult ... WebTherefore, the weekly dosage of a drug can be approximately the same in CAPD patients and hemodialysis patients, and dosing design for patients with a pre-end-stage renal disease in the period prior to the initiation of dialysis can be applied to CAPD patients. Nevertheless, an appropriate dosage regimen, based on drug clearance, should be ... crystal family resort \u0026 spa hotel